Myopia, or nearsightedness, is becoming more common, especially among kids. As of 2020, approximately 2.64 billion people worldwide are myopic, which accounts for 33.9% of the global population of 7.79 billion.
In Canada, a pilot study conducted in the Kitchener-Waterloo region found that the overall prevalence of myopia among school children was 17.5%. This included 6.0% of children aged 6-8 and 28.9% of those aged 11-13.
Parents are worried and wondering what can be done to slow it down. One treatment that’s been generating interest is atropine eye drops. These eye drops contain different concentrations and don’t work the same way. There’s been a lot of buzz lately around two concentrations in particular: 0.05% and 0.01%.
So, how do they compare when controlling myopia progression? Well, some of the latest studies are trying to figure that out, and the findings are eye-opening! Let’s look into what these studies reveal about the effectiveness of these two options and what they could mean for kids with myopia.
What Is Atropine Therapy?

Atropine therapy is a treatment for slowing down myopia progression, especially in children. It involves using special eye drops that contain a low dose of atropine, a medication that helps relax certain muscles in the eye and affects how it focuses.
The goal is to reduce how quickly myopia gets worse over time. Unlike the stronger versions of atropine used for other eye conditions, the low doses used in myopia control (eg: 0.01% or 0.05%) are much gentler and are designed to minimize side effects, such as light sensitivity or difficulty focusing on close objects.
Comparative Effectiveness: Atropine 0.05% vs. 0.01%

A recent study has shed new light on controlling myopia in children, revealing that a 0.05% concentration of atropine is more effective than the widely used 0.01% for slowing myopia progression without compromising quality of life.
Myopia, a condition where the eyeball elongates, causing blurry distance vision, is becoming increasingly common worldwide, and experts predict half the global population may be affected by 2050.
This study, an extension of the LAMP (Low-concentration Atropine for Myopia Progression) trial, followed 383 children aged 4 to 12 over two years. Participants were given daily atropine at concentrations of 0.05%, 0.025%, 0.01%, or a placebo.
Researchers measured changes in spherical equivalent (SE) and axial length (AL) every four months, key indicators of myopia progression.
The findings were clear: the 0.05% group showed significantly less SE progression (0.55 D) and AL change (0.39 mm) compared to the 0.01% group, which saw more progression (1.12 D SE and 0.59 mm AL). Despite concerns about side effects, no adverse impacts on visual acuity or quality of life were observed with the 0.05% concentration, making it the most effective option for longer-term control.
Benefits of Atropine 0.05% Over 0.01%

When managing myopia in children, choosing the right concentration of atropine can make a significant difference. Here are some key benefits of using atropine 0.05% over the 0.01% concentration:
1. Greater Effectiveness in Slowing Myopia Progression
Studies have shown that atropine 0.05% is generally more effective at reducing myopia progression rate than 0.01%. This means that children using the higher concentration may experience less worsening of their vision over time.
2. Improved Control Over Myopia
The 0.05% concentration might provide better overall control for children with rapidly progressing myopia. This is particularly important for kids who may have a higher risk of developing severe myopia as they grow older.
3. Shorter Treatment Duration
Since 0.05% atropine tends to be more effective, it may allow for a shorter duration of treatment needed to achieve desired results. This can be especially appealing for parents and children looking for more straightforward management of myopia.
4. Potential for Long-Term Benefits
By better controlling myopia progression, the 0.05% concentration may help reduce the risk of associated complications later in life, such as retinal detachment or glaucoma, which are more common in individuals with high myopia.
5. Flexible Dosing
With a greater potency of 0.05%, eye care providers may have more flexibility in adjusting treatment plans based on individual responses. Moving to a higher concentration could offer a straightforward solution if a child is not responding adequately to 0.01%
6. High Acceptance
Many children tolerate atropine 0.05% well, and while it may have some side effects, these are often manageable. The potential benefits outweigh the discomfort for families seeking effective treatment options.
The Treatment Process with Atropine

The treatment process with Atropine for managing myopia is actually quite simple, though there’s a lot more to it than just putting drops in your eyes. It’s a low-dose eye drop, usually prescribed in concentrations like 0.05% or 0.01%, and it works by slowing down the growth of the eye, which leads to myopia progression.
Your optometrist will start by explaining how to use the drops—typically, you or your child will need to apply them once before bed. Atropine drops help relax the focusing muscles in the eye, and over time, this can reduce the rapid progression of nearsightedness.
The good thing is that the drops are easy to use, and side effects like light sensitivity or trouble reading up close are usually mild or absent with these lower doses.
If you see Toronto optometrists familiar with myopia therapy, they’ll also monitor progress closely. Regular follow-ups will track how well the treatment is working and make adjustments if necessary. This means you’ll likely have eye exams every few months, ensuring the therapy is doing its job and myopia is under control.
It’s not a one-size-fits-all process—Atropine may be paired with other treatments, like special glasses or contact lenses, to give you or your child the best chance of managing myopia effectively
Potential Challenges and Considerations
When it comes to treating myopia with Atropine, there are a few potential challenges and considerations to keep in mind. One of the first things Toronto optometrists often point out is that not everyone responds to myopia therapy in the same way.
While Atropine can be very effective in slowing myopia progression, the exact results can vary depending on individual factors, such as age, the severity of myopia, and the consistency of use. Similar variations are often observed with other common vision issues, as explored in various eye conditions and their corresponding treatments.
There’s also the question of side effects, though they tend to be mild with low-dose Atropine. Some patients might experience light sensitivity or blurred near vision, which can be managed with sunglasses outdoors or by using reading glasses. But it’s important to remember this, especially for younger children who might not always be able to express discomfort.
Another consideration is the commitment to regular follow-ups. Since myopia can change as children grow, sticking to those scheduled eye exams is crucial. This lets your optometrist see how well the therapy works and make adjustments if needed. For parents, this might require some extra time and effort, but it’s vital to ensuring the therapy’s long-term success.
Lastly, cost and accessibility can sometimes pose a challenge. Not all insurance plans cover Atropine therapy for myopia, and depending on where you’re getting treatment in Toronto, it might take some time to find a clinic that offers it. However, given the long-term benefits of slowing down myopia progression, many find that it’s worth the investment.
We offer flexible payment plans to all our patients and customers through Affirm. Contact us to learn more
When should I see a doctor about myopia?

If you or your child is noticing that things in the distance are becoming blurry, or if squinting has become second nature just to read a sign, it’s time to see a doctor about myopia. Myopia often develops in childhood and tends to worsen as kids grow, so catching it early and starting myopia therapy can make a big difference in managing its progression.
While some parents may feel unsure if it’s serious enough to warrant a visit, regular eye exams ensure proper eye health, especially with myopia becoming more common.
If you’re in Toronto, optometrists at 360 Eyecare can help guide you through diagnosing and managing myopia. Many families begin their search with terms like Optometry Near Me, which makes finding trusted care easier and more accessible. With two convenient locations in the Yorkville neighborhood and The Beaches, our experienced professionals are ready to provide personalized care and solutions to your or your child’s needs.
Read More on options for controlling Myopia
Conclusion
As the saying goes, “Prevention is better than cure.” When it comes to myopia, early detection and treatment are crucial for managing its progression, especially in children. Whether you’re an adult or bringing in your child, regular eye exams can make all the difference in preserving long-term vision and ensuring eye health stays on track.
Frequently Asked Questions
How Effective Is Atropine 0.05% Compared to 0.01%?
Atropine 0.05% is generally more effective than 0.01% in slowing myopia progression. While both concentrations help, studies indicate that higher doses yield better results, but individual responses may vary.
Are There Any Side Effects?
Yes, side effects can occur but are typically mild. Common ones include light sensitivity and blurred near vision. Most individuals adapt well, and sunglasses can help manage light sensitivity, especially for children.
What Are the Long-Term Implications of Using Atropine?
Long-term use of Atropine can effectively slow myopia progression, potentially reducing the risk of serious eye conditions later. Regular check-ups are essential to monitor any side effects and ensure the continued effectiveness of the treatment.
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